Last time both sides faced each other, Hearts B secured a convincing three points at home on the opening day of the season – thanks to a 7-0 win at Ainslie Park.
Gretna 2008 currently sit second-bottom of the table with eight points from their 29 games played – made up of two wins, two draws, and 25 defeats.
Since their 6-0 win over Lochmaben in the Potts Cup, the Anvils come into this following six-straight defeats.
Hearts B currently sit in 2nd place with 60 points from their 30 games played – made up of 18 wins, six draws, and six defeats.
The Wee Jambos come into this off the back of a five-game winning streak – defeating Tranent, East Kilbride, Albion Rovers, Broomhill, and Linlithgow Rose.