The last time both sides faced each other, it was Celtic B that secured the three points – thanks to a 4-0 victory at home.
Edinburgh University currently sit bottom of the table with five points from their 21 games played – made up of one win, two draws, and 18 defeats.
Uni have lost their last four matches, conceding 24 goals, and scoring two – coming in fresh off the 12-0 defeat to Hearts B.
Celtic B currently sit in 9th place with 30 points from their 21 games played – made up of nine wins, three draws, and nine defeats.
The Young Hoops are undefeated in their last three matches – with 7-0 and 2-0 wins coming against Gretna 2008 and Broomhill. Their recent match saw them score a late equaliser to secure a 3-3 draw against Gretna 2008 at Raydale.